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547 Main St, Danville, VA 24541
1/2 LB of Our Famous Catfish. Served with Seasoned Fries, 2 oz. Coleslaw, and Nana Karen's Old Bay Tartar.
1/2 LB of Our Famous Catfish. Served with Seasoned Fries, 2 oz. Coleslaw, and Nana Karen's Old Bay Tartar.
It's in the name. Our Creamy Yellow Mac & Cheese Topped with Chopped Buffalo Tenders, Blow Torched White Cheddar Cheese, Diced Tomatoes, and Green Onions
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For those that are a little less adventurous! Four tenders served with krinkle cut fries and choice of ranch, honey mustard, or BBQ sauce. Note if you want your tenders in Buffalo or BBQ!
For those that are a little less adventurous! Four tenders served with krinkle cut fries and choice of ranch, honey mustard, or BBQ sauce. Note if you want your tenders in Buffalo or BBQ!
Our Power Plate filled with Cilantro Rice, Grilled Chicken, Mexican Sausage, Grilled Bell Peppers and Onions, Diced Tomatoes, and finished with our House Bang Bang Sauce.
Hibachi done our way! Choice of Chicken or Shrimp Over Fried Rice in our House Citrus Soy & Teriyaki Sauce, Tossed with Fresh Zucchini, Squash, and Chopped Onion. Served with Bang Bang Sauce on the side.
Our signature Mac and Cheese loaded with Andouille Sausage. Finished with Diced Tomatoes, and Fresh Scallions
Chorizo with Fried Egg, Seasoned Fries, and Sour Cream in Our Cheddar Tortilla. Served with Hot Sauce on the Side.
Fried Chicken Tenders, Duke's Mayonnaise, Lettuce, Tomato, Crispy Bacon, Sweet Baby Rays BBQ Sauce, and a Three Cheese Blend
Diced Fried Chicken, Bacon, Shredded Lettuce, and Diced Tomato. Finished with Creamy Ranch Dressing and a Three Cheese Blend
Homemade White Cheddar Mac and Cheese Stuffed Between Two slices of Grilled Sourdough
Diced Fried Chicken, Bacon, Shredded Lettuce, and Diced Tomato. Finished with Creamy Ranch Dressing and a Three Cheese Blend
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Download MacrosMap →Cinnamon Sourdough, Homemade Strawberry Compote, Nana’s Cream Cheese Icing, and a hint of Balsamic Glaze
Stuffed with Fried Chicken Tenders, House Bang Bang Sauce, Lettuce, Tomato, Green Onions, and White Cheddar Cheese.
Half Cheesecake, Half Banana Pudding! Katies’s Homemade Cheesecake Bowls! *If we are out of stock here, try next door at Cheyna’s Waffle Spot!*
Fried Chicken Strips, Louisiana Hot Sauce, Creamy Ranch Dressing, Cheddar Jack Cheese, Shredded Lettuce, and Diced Tomato served in a Jalapeño Cheddar Tortilla
With our fish being so popular, it was only right that we perfected our Cajun Breading for Chicken too! Served on a Kaiser Roll with Lettuce, Tomato, and House Chipoltle Mayo
Fried Chicken Strips, House Raspberry Walnut Vinaigrette, Three-Cheese Blend, Shredded Lettuce, and Diced Tomato served in a Cheddar Tortilla
The Sandwich that made us Locally Famous. This Tasty Southern Classic is Hand Breaded and Served with Lettuce, Tomato, and Homemade Old Bay Tartar Sauce
Hand-breaded and Flash Fried. Served on Toasted Maple Sourdough with Iceberg Lettuce, Crispy Bacon, and Chipotle Mayo
Jamaican Herb-Roasted Chicken, Garlic Roasted Peppers and Onions, Blackberry Aioli, Shredded Lettuce, Diced Tomatoes, and shredded cheese served in a Cheddar Tortilla
Our Citrus Soy Hibachi Rice with Roasted Red Peppers & Broccoli. Finished on the Grill with Our Signature Mandarin Compote. Served with Bang Bang Sauce on the side.
Katies’s Homemade Cheesecake Bowls! If we are out of stock here, try next door at Cheyna’s Waffle Spot!
The Sandwich that made us Locally Famous. This Tasty Southern Classic is Hand Breaded and Served with Lettuce, Tomato, and Homemade Old Bay Tartar Sauce
Cooked to order three egg omelette stuffed with our Corned Beef Hash and a Three cheese blend. Finished with Fresh Greens and Roasted Red Peppers
Maple Grilled Chicken, Crispy Bacon, Spring mix, Roasted Red Peppers, and Feta Cheese stuffed in our Cheddar Tortilla with Blackberry Aioli
Crispy Bacon, Fried Tomatoes, Spring Mix, and Duke’s Mayonnaise on Grilled Sourdough
Bacon, Egg, and Cheese Served on a Toasted Everything Bagel.
Note whether you want with a side of Marinara or Ranch!
Pasta Salad
Potato Salad
Fries
Baked beans
Slaw
Broccoli
Discover the nutritional content of menu items at Nana Karen's on Main in Danville, VA. Our comprehensive nutrition database provides detailed calorie counts and macronutrient breakdowns (protein, carbohydrates, and fat) for each menu item.
Whether you're tracking macros, counting calories, or simply making healthier dining choices, our nutrition facts help you make informed decisions when eating out. All nutritional values are estimates based on typical ingredients and preparation methods.
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Macros Menu. "Nana Karen's on Main Menu - Nutrition Facts – Macros & Calories." https://macros.menu/nana-karens-on-main-danville-va. Accessed December 31, 2025.